ST上昇型急性心筋梗塞の診療に関するガイドライン（2013年改訂版）
Guidelines for the management of patients with ST-elevation acute myocardial infarction
（JCS 2013）
文献
701. Oh JK, Appleton CP, Hatle LK, et al. The noninvasive assessment of left ventricular diastolic function with two-dimensional and Doppler
echocardiography. J Am Soc Echocardiogr 1997; 10: 246-270.
702. Nijland F, Kamp O, Karreman AJ, et al. Prognostic implications of restrictive left ventricular filling in acute myocardial infarction: a serial Doppler
echocardiographic study. J Am Coll Cardiol 1997; 30: 1618-1624.
703. Sakata K, Kashiro S, Hirata S, et al. Prognostic value of Doppler transmitral flow velocity patterns in acute myocardial infarction. Am J Cardiol
1997; 79: 1165-1169.
704. Cerisano G, Bolognese L, Buonamici P, et al. Prognostic implications of restrictive left ventricular filling in reperfused anterior acute myocardial
infarction. J Am Coll Cardiol 2001; 37: 793-799.
705. Hillis GS, Moller JE, Pellikka PA, et al. Noninvasive estimation of left ventricular filling pressure by E/e' is a powerful predictor of survival after acute
myocardial infarction. J Am Coll Cardiol 2004; 43: 360-367.
706. Lamas GA, Mitchell GF, Flaker GC, et al. Clinical significance of mitral regurgitation after acute myocardial infarction. Survival and Ventricular
Enlargement Investigators. Circulation 1997; 96: 827-833.
707. Grigioni F, Enriquez-Sarano M, Zehr KJ, et al. Ischemic mitral regurgitation: long-term outcome and prognostic implications with quantitative Doppler
assessment. Circulation 2001; 103: 1759-1764.
708. Bursi F, Enriquez-Sarano M, Nkomo VT, et al. Heart failure and death after myocardial infarction in the community: the emerging role of mitral
regurgitation. Circulation 2005; 111: 295-301.
709. Moller JE, Hillis GS, Oh JK, et al. Prognostic importance of secondary pulmonary hypertension after acute myocardial infarction. Am J Cardiol
2005; 96: 199-203.
710. Obeidat O, Alam M, Divine GW, et al. Echocardiographic predictors of prognosis after first acute myocardial infarction. Am J Cardiol 2004; 94:
1278-1280.
711. St John Sutton M, Pfeffer MA, Plappert T, et al. Quantitative two-dimensional echocardiographic measurements are major predictors of adverse
cardiovascular events after acute myocardial infarction. The protective effects of captopril. Circulation 1994; 89: 68-75.
712. Moller JE, Hillis GS, Oh JK, et al. Left atrial volume: a powerful predictor of survival after acute myocardial infarction. Circulation 2003; 107: 2207-2212.
713. Beinart R, Boyko V, Schwammenthal E, et al. Long-term prognostic significance of left atrial volume in acute myocardial infarction. J Am Coll Cardiol
2004; 44: 327-334.
714. Bigi R, Cortigiani L, Mariani PR, et al. Sustained favorable long-term prognosis of negative stress echocardiography following uncomplicated
myocardial infarction. Am J Cardiol 2002; 90: 149-152.
715. Swinburn JM, Senior R. Myocardial viability assessed by dobutamine stress echocardiography predicts reduced mortality early after acute myocardial
infarction: determining the risk of events after myocardial infarction (DREAM) study. Heart 2006; 92: 44-48.
716. Nijland F, Kamp O, Verhorst PM, et al. Early prediction of improvement in ejection fraction after acute myocardial infarction using low dose dobutamine
echocardiography. Heart 2002; 88: 592-596.
717. Desideri A, Fioretti PM, Cortigiani L, et al. Cost of strategies after myocardial infarction (COSTAMI): a multicentre, international, randomized trial for
cost-effective discharge after uncomplicated myocardial infarction. Eur Heart J 2003; 24: 1630-1639.
718. Desideri A, Fioretti PM, Cortigiani L, et al. Pre-discharge stress echocardiography and exercise ECG for risk stratification after uncomplicated acute
myocardial infarction: results of the COSTAMI-II (cost of strategies after myocardial infarction) trial. Heart 2005; 91: 146-151.
719. Allman KC, Shaw LJ, Hachamovitch R, et al. Myocardial viability testing and impact of revascularization on prognosis in patients with coronary artery
disease and left ventricular dysfunction: a meta-analysis. J Am Coll Cardiol 2002; 39: 1151-1158.
720. Gibbons RJ, Chatterjee K, Daley J, et al. ACC/AHA/ACP-ASIM guidelines for the management of patients with chronic stable angina: a report of the
American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Patients With
Chronic Stable Angina). J Am Coll Cardiol 1999; 33: 2092-2197.
721. Olona M, Candell-Riera J, Permanyer-Miralda G, et al. Strategies for prognostic assessment of uncomplicated first myocardial infarction: 5-year
follow-up study. J Am Coll Cardiol 1995; 25: 815-822.
722. Mahmarian JJ, Mahmarian AC, Marks GF, et al. Role of adenosine thallium-201 tomography for defining long-term risk in patients after acute
myocardial infarction. J Am Coll Cardiol 1995; 25: 1333-1340.
723. Hung J, Moshiri M, Groom GN, et al. Dipyridamole thallium-201 scintigraphy for early risk stratification of patients after uncomplicated myocardial
infarction. Heart 1997; 78: 346-352.
724. Iskander S, Iskandrian AE. Risk assessment using single-photon emission computed tomographic technetium-99m sestamibi imaging. J Am Coll
Cardiol 1998; 32: 57-62.
725. Hachamovitch R, Berman DS, Shaw LJ, et al. Incremental prognostic value of myocardial perfusion single photon emission computed tomography for
the prediction of cardiac death: differential stratification for risk of cardiac death and myocardial infarction. Circulation 1998; 97: 535-543.
726. Acampa W, Spinelli L, Petretta M, et al. Comparison of prognostic value of negative dobutamine stress echocardiography versus single-photon
emission computed tomography after acute myocardial infarction. Am J Cardiol 2005; 96: 13-16.
727. Nakayama M, Tanno M, Yamada H, et al. Correlation of diagnostic accuracy of dipyridamole thallium-201 myocardial scintigraphy and clinical
findings during stress. Jpn Heart J 1994; 35: 281-294.
728. Franken PR, Dendale P, De Geeter F, et al. Prediction of functional outcome after myocardial infarction using BMIPP and sestamibi scintigraphy.
J Nucl Med 1996; 37: 718-722.
729. Fujiwara S, Takeishi Y, Atsumi H, et al. Prediction of functional recovery in acute myocardial infarction: comparison between sestamibi reverse
redistribution and sestamibi/BMIPP mismatch. J Nucl Cardiol 1998; 5: 119-127.
730. Beek AM, Kuhl HP, Bondarenko O, et al. Delayed contrastenhanced magnetic resonance imaging for the prediction of regional functional improvement
after acute myocardial infarction. J Am Coll Cardiol 2003; 42: 895-901.
731. Lombardi M, Kvaerness J, Torheim G, et al. Relationship between function and perfusion early after acute myocardial infarction. Int J Cardiovasc
Imaging 2001; 17: 383-393.
732. Beanlands RS, Nichol G, Huszti E, et al. F-18-fluorodeoxyglucose positron emission tomography imaging-assisted management of patients with
severe left ventricular dysfunction and suspected coronary disease: a randomized, controlled trial (PARR-2). J Am Coll Cardiol 2007; 50: 2002-2012.
733. La Canna G, Rahimtoola SH, Visioli O, et al. Sensitivity, specificity, and predictive accuracies of non-invasive tests, singly and in combination, for
diagnosis of hibernating myocardium. Eur Heart J 2000; 21: 1358-1367.
734. Risk stratification and survival after myocardial infarction. N Engl J Med 1983; 309: 331-336.
735. Urena PE, Lamas GA, Mitchell G, et al. Ejection fraction by radionuclide ventriculography and contrast left ventriculogram. A tale of two techniques.
SAVE Investigators. Survival and Ventricular Enlargement. J Am Coll Cardiol 1999; 33: 180-185.
736. Rashid H, Exner DV, Mirsky I, et al. Comparison of echocardiography and radionuclide angiography as predictors of mortality in patients with left
ventricular dysfunction (studies of left ventricular dysfunction). Am J Cardiol 1999; 84: 299-303.
737. La Rovere MT, Bigger JT, Marcus FI, et al. Baroreflex sensitivity and heart-rate variability in prediction of total cardiac mortality after myocardial
infarction. ATRAMI (Autonomic Tone and Reflexes After Myocardial Infarction) Investigators. Lancet 1998; 351: 478-484.
738. Wilber DJ, Zareba W, Hall WJ, et al. Time dependence of mortality risk and defibrillator benefit after myocardial infarction. Circulation 2004; 109: 1082-
1084.
739. Hamer AW, Takayama M, Abraham KA, et al. End-systolic volume and long-term survival after coronary artery bypass graft surgery in patients with
impaired left ventricular function. Circulation 1994; 90: 2899-2904.
740. Connolly SJ, Gent M, Roberts RS, et al. Canadian implantable defibrillator study (CIDS): a randomized trial of the implantable cardioverter defibrillator
against amiodarone. Circulation 2000; 101: 1297-1302.
741. Moss AJ, Hall WJ, Cannom DS, et al. Improved survival with an implanted defibrillator in patients with coronary disease at high risk for ventricular
arrhythmia. Multicenter Automatic Defibrillator Implantation Trial Investigators. N Engl J Med 1996; 335: 1933-1940.
742. A comparison of antiarrhythmic-drug therapy with implantable defibrillators in patients resuscitated from near-fatal ventricular arrhythmias. The
Antiarrhythmics versus Implantable Defibrillators (AVID) Investigators. N Engl J Med 1997; 337: 1576-1583.
743. Kuck KH, Cappato R, Siebels J, et al. Randomized comparison of antiarrhythmic drug therapy with implantable defibrillators in patients resuscitated
from cardiac arrest : the Cardiac Arrest Study Hamburg (CASH). Circulation 2000; 102: 748-754.
744. Paelinck BP, Vrints CJ, Bax JJ, et al. Relation of B-type natriuretic peptide early after acute myocardial infarction to left ventricular diastolic function
and extent of myocardial damage determined by magnetic resonance imaging. Am J Cardiol 2006; 97: 1146-1150.
745. Richards AM, Nicholls MG, Espiner EA, et al. B-type natriuretic peptides and ejection fraction for prognosis after myocardial infarction. Circulation
2003; 107: 2786-2792.
746. Suzuki S, Yoshimura M, Nakayama M, et al. Plasma level of B-type natriuretic peptide as a prognostic marker after acute myocardial infarction:
a long-term follow-up analysis. Circulation 2004; 110: 1387-1391.
747. Omland T, Persson A, Ng L, et al. N-terminal pro-B-type natriuretic peptide and long-term mortality in acute coronary syndromes. Circulation 2002;
106: 2913-2918.
748. Lee JH, Park HS, Chae SC, et al. Predictors of six-month major adverse cardiac events in 30-day survivors after acute myocardial infarction (from the
Korea Acute Myocardial Infarction Registry). Am J Cardiol 2009; 104: 182-189.
749. Kinjo K, Sato H, Sakata Y, et al. Osaka Acute Coronary Insufficiency Study (OACIS) Group. Relation of C-reactive protein and one-year survival after
acute myocardial infarction with versus without statin therapy. Am J Cardiol 2005; 96: 617-621.
750. Ang DS, Kao MP, Dow E, et al. The prognostic value of high sensitivity troponin T 7 weeks after an acute coronary syndrome. Heart 2012; 98: 1160-
1165.
751. Matsumoto S, Nakatani D, Sakata Y, et al. Elevated serum heart-type fatty acid-binding protein in the convalescent stage predicts long-term outcome
in patients surviving acute myocardial infarction. Circ J 2013; 77: 1026-1032.
752. Hara M, Sakata Y, Nakatani D, et al. Low levels of serum n-3 polyunsaturated fatty acids are associated with worse heart failure-free survival in
patients after acute myocardial infarction. Circ J 2013; 77: 153-162.
753. Matsumoto S, Sakata Y, Nakatani D, et al. A subset of circulating microRNAs are predictive for cardiac death after discharge for acute myocardial
infarction. Biochem Biophys Res Commun 2012; 427: 280-284.
754. Ross J, Gilpin EA, Madsen EB, et al. A decision scheme for coronary angiography after acute myocardial infarction. Circulation 1989; 79: 292-303.
755. Moss AJ, Zareba W, Hall WJ, et al. Prophylactic implantation of a defibrillator in patients with myocardial infarction and reduced ejection fraction.
N Engl J Med 2002; 346: 877-883.
756. Hohnloser SH, Kuck KH, Dorian P, et al. Prophylactic use of an implantable cardioverter-defibrillator after acute myocardial infarction. N Engl J Med
2004; 351: 2481-2488.
757. Bailey JJ, Berson AS, Handelsman H, et al. Utility of current risk stratification tests for predicting major arrhythmic events after myocardial infarction.
J Am Coll Cardiol 2001; 38: 1902-1911.
758. Maggioni AP, Zuanetti G, Franzosi MG, et al. Prevalence and prognostic significance of ventricular arrhythmias after acute myocardial infarction in the
fibrinolytic era. GISSI-2 results. Circulation 1993; 87: 312-322.
759. Zuanetti G, Neilson JM, Latini R, et al. Prognostic significance of heart rate variability in post-myocardial infarction patients in the fibrinolytic era. The
GISSI-2 results. Gruppo Italiano per lo Studio della Sopravvivenza nell' Infarto Miocardico. Circulation 1996; 94: 432-436.
760. Malik M, Camm AJ, Janse MJ, et al. Depressed heart rate variability identifies postinfarction patients who might benefit from prophylactic treatment
with amiodarone: a substudy of EMIAT (The European Myocardial Infarct Amiodarone Trial). J Am Coll Cardiol 2000; 35: 1263-1275.
761. Makikallio TH, Barthel P, Schneider R, et al. Prediction of sudden cardiac death after acute myocardial infarction: role of Holter monitoring in the
modern treatment era. Eur Heart J 2005; 26: 762-769.
762. Denes P, el-Sherif N, Katz R, et al. Prognostic significance of signal-averaged electrocardiogram after thrombolytic therapy and/or angioplasty during
acute myocardial infarction (CAST substudy). Cardiac Arrhythmia Suppression Trial (CAST) SAECG Substudy Investigators. Am J Cardiol 1994; 74:
216-220.
763. el-Sherif N, Denes P, Katz R, et al. Definition of the best prediction criteria of the time domain signal-averaged electrocardiogram for serious arrhythmic
events in the postinfarction period. The Cardiac Arrhythmia Suppression Trial/Signal-Averaged Electrocardiogram (CAST/SAECG) Substudy
Investigators. J Am Coll Cardiol 1995; 25: 908-914.
764. Hohnloser SH, Ikeda T, Bloomfield DM, et al. T-wave alternans negative coronary patients with low ejection and benefit from defibrillator implantation.
Lancet 2003; 362: 125-126.
765. Zoni-Berisso M, Molini D, Mela GS, et al. Value of programmed ventricular stimulation in predicting sudden death and sustained ventricular tachycardia
in survivors of acute myocardial infarction. Am J Cardiol 1996; 77: 673-680.
766. Buxton AE, Lee KL, Fisher JD, et al. A randomized study of the prevention of sudden death in patients with coronary artery disease. Multicenter
Unsustained Tachycardia Trial Investigators. N Engl J Med 1999; 341: 1882-1890.
767. Daubert JP, Zareba W, Hall WJ, et al. Predictive value of ventricular arrhythmia inducibility for subsequent ventricular tachycardia or ventricular
fibrillation in Multicenter Automatic Defibrillator Implantation Trial (MADIT) II patients. J Am Coll Cardiol 2006; 47: 98-107.
768. Nakatani D, Sakata Y, Sato H, et al. Osaka Acute Coronary Insufficiency Study (OACIS) Group. Clinical impact of metabolic syndrome and its
additive effect with smoking on subsequent cardiac events after acute myocardial infarction. Am J Cardiol 2007; 99: 885-889.
769. Nakatani D, Sakata Y, Suna S, et al; Osaka Acute Coronary Insufficiency Study (OACIS) Investigators. Incidence, predictors, and subsequent
mortality risk of recurrent myocardial infarction in patients following discharge for acute myocardial infarction. Circ J 2013; 77: 439-446.
770. Balady GJ, Fletcher BJ, Froelicher EF, et al. Cardiac rehabilitation programs: a statement for healthcare professionals from the American Heart
Association. Circulation 1994; 90: 1602-1610.
771. Wenger NK, Froelicher ES, Smith LK, et al. Clinical Practice Guidelines No. 17: Cardiac Rehabilitation as Secondary Prevention. U.S. Department of
Health and Human Services, Public Health Service, Agency for Health Care Policy and Research, National Heart, Lung and Blood Institute, 1995.
AHCPR Publication 96-0672.
772. Leon AS, Franklin BA, Costa F, et al. Cardiac rehabilitation and secondary prevention of coronary heart disease: an American Heart Association
scientific statement from the Council on Clinical Cardiology (Subcommittee on Exercise, Cardiac Rehabilitation, and Prevention) and the Council on
Nutrition, Physical Activity, and Metabolism (Subcommittee on Physical Activity), in collaboration with the American association of Cardiovascular
and Pulmonary Rehabilitation. Circulation 2005; 111: 369-376.
773. Ades PA. Cardiac rehabilitation and secondary prevention of coronary heart disease. N Engl J Med 2001; 345: 892-902.
774. Taylor RS, Brown A, Ebrahim S, et al. Exercise-based rehabilitation for patients with coronary heart disease: systematic review and meta-analysis of
randomized controlled trials. Am J Med 2004; 116: 682-692.
775. Lawler PR, Filion KB, Eisenberg MJ. Efficacy of exercise-based cardiac rehabilitation post-myocardial infarction: a systematic review and meta-
analysis of randomized controlled trials. Am Heart J 2011; 162: 571-584.e572.
776. Haykowsky M, Scott J, Esch B, et al. A meta-analysis of the effects of exercise training on left ventricular remodeling following myocardial infarction:
start early and go longer for greatest exercise benefits on remodeling. Trials 2011; 12: 92.
777. Antman EM, Hand M, Armstrong PW, et al. 2007 Focused Update of the ACC/AHA 2004 Guidelines for the Management of Patients With
ST-Elevation Myocardial Infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines:
developed in collaboration With the Canadian Cardiovascular Society endorsed by the American Academy of Family Physicians: 2007 Writing Group
to Review New Evidence and Update the ACC/AHA 2004 Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction, Writing
on Behalf of the 2004 Writing Committee. Circulation 2008; 117: 296-329.
778. Smith SC, Benjamin EJ, Bonow RO, et al. AHA/ACCF Secondary Prevention and Risk Reduction Therapy for Patients with Coronary and other
Atherosclerotic Vascular Disease: 2011 update: a guideline from the American Heart Association and American College of Cardiology Foundation.
Circulation 2011; 124: 2458-2473.
779. Yoshida T, Yoshida K, Yamamoto C, et al. Effects of a two-week, hospitalized phase II cardiac rehabilitation program on physical capacity, lipid
profiles and psychological variables in patients with acute myocardial infarction. Jpn Circ J 2001; 65: 87-93.
780. 循環器病の診断と治療に関するガイドライン．心血管疾患におけるリハビリテーションに関するガイドライン（2007年改訂版）．http://www.j-
circ.or.jp/guideline/pdf/JCS2007_nohara_d.pdf（2012年12月閲覧）
781. Izawa K, Hirano Y, Yamada S, et al. Improvement in physiological outcomes and health-related quality of life following cardiac rehabilitation in
patients with acute myocardial infarction. Circ J 2004; 68: 315-320.
782. Suzuki S, Takaki H, Yasumura Y, et al. Assessment of quality of life with 5 different scales in patients participating in comprehensive cardiac
rehabilitation after acute myocardial infarction. Circ J 2005; 69: 1527-1534.
783. Kida K, Osada N, Akashi YJ, et al. The exercise training effects of skeletal muscle strength and muscle volume to improve functional capacity in
patients with myocardial infarction. Int J Cardiol 2008; 129: 180-186.
784. Sumide T, Shimada K, Ohmura H, et al. Relationship between exercise tolerance and muscle strength following cardiac rehabilitation: comparison
of patients after cardiac surgery and patients with myocardial infarction. J Cardiol 2009; 54: 273-281.
785. Kamakura T, Kawakami R, Nakanishi M, et al. Efficacy of out-patient cardiac rehabilitation in low prognostic risk patients after acute myocardial
infarction in primary intervention era. Circ J 2011; 75: 315-321.
786. Goto Y, Itoh H, Adachi H, et al. Use of exercise cardiac rehabilitation after acute myocardial infarction. Circ J 2003; 67: 411-415.
787. Goto Y, Saito M, Iwasaka T, et al. Poor implementation of cardiac rehabilitation despite broad dissemination of coronary interventions for acute
myocardial infarction in Japan: a nationwide survey. Circ J 2007; 71: 173-179.
788. 中西道郎，長山雅俊，安達仁，他．我が国における急性心筋梗塞後心臓リハビリテーション実施率の動向：全国実態調査．心臓リハ 2011; 16: 188-192.
789. Fletcher GF, Balady GJ, Amsterdam EA, et al. Exercise standards for testing and training: a statement for healthcare professionals from the
American Heart Association. Circulation 2001; 104: 1694-1740.
790. Sanderson BK, Southard D, Oldridge N, et al. AACVPR consensus statement. Outcomes evaluation in cardiac rehabilitation/secondary prevention
programs: improving patient care and program effectiveness. J Cardiopulm Rehabil 2004; 24: 68-79.
791. Balady GJ, Williams MA, Ades PA, et al. AHA/AACVPR Scientific Statement. Core components of cardiac rehabilitation/ secondary prevention
programs: 2007 Update. A Scientific Statement From the American Heart Association Exercise, Cardiac Rehabilitation, and Prevention Committee,
the Council on Clinical Cardiology; the Councils on Cardiovascular Nursing, Epidemiology and Prevention, and Nutrition, Physical Activity, and
Metabolism; and the American Association of Cardiovascular and Pulmonary Rehabilitation. Circulation 2007; 115: 2675-2682.
792. Chobanian AV, Lille RD, Tercyak A, et al. The metabolic and hemodynamic effects of prolonged bed rest in normal subjects. Circulation 1974; 49:
551-559.
793. Cannon CP, Hand MH, Bahr R, et al. Critical pathways for management of patients with acute coronary syndromes: an assessment by the National
Heart Attack Alert Program. Am Heart J 2002; 143: 777-789.
794. 循環器病の診断と治療に関するガイドライン．心血管疾患におけるリハビリテーションに関するガイドライン（2012年改訂版）．http://www.j-
circ.or.jp/guideline/pdf/JCS2012_nohara_h.pdf（2012年12月閲覧）
795. Gibbons RJ, Balady GJ, Bricker JT, et al. ACC/AHA 2002 guideline update for exercise testing: summary article: a report of the American College of
Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Update the 1997 Exercise Testing Guidelines). Circulation
2002; 106: 1883-1892.
796. Senaratne MP, Smith G, Gulamhusein SS. Feasibility and safety of early exercise testing using the Bruce protocol after acute myocardial infarction.
J Am Coll Cardiol 2000; 35: 1212-1220.
797. Goto Y, Sumida H, Ueshima K, et al. Safety and implementation of exercise testing and training after coronary stenting in patients with acute
myocardial infarction. Circ J 2002; 66: 930-936.
798. Williams MA, Haskell WL, Ades PA, et al. Resistance exercise in individuals with and without cardiovascular disease: 2007 update: a scientific
statement from the American Heart Association Council on Clinical Cardiology and Council on Nutrition, Physical Activity, and Metabolism.
Circulation 2007; 116: 572-584.
799. Wilke NA, Sheldahl LM, Tristani FE, et al. The safety of staticdynamic effort soon after myocardial infarction. Am Heart J 1985; 110: 542-545.
800. Arthur HM, Gunn E, Thorpe KE, et al. Effect of aerobic vs combined aerobic-strength training on 1-year, post-cardiac rehabilitation outcomes in
women after a cardiac event. J Rehabil Med 2007; 39: 730-735.
echocardiography. J Am Soc Echocardiogr 1997; 10: 246-270.
702. Nijland F, Kamp O, Karreman AJ, et al. Prognostic implications of restrictive left ventricular filling in acute myocardial infarction: a serial Doppler
echocardiographic study. J Am Coll Cardiol 1997; 30: 1618-1624.
703. Sakata K, Kashiro S, Hirata S, et al. Prognostic value of Doppler transmitral flow velocity patterns in acute myocardial infarction. Am J Cardiol
1997; 79: 1165-1169.
704. Cerisano G, Bolognese L, Buonamici P, et al. Prognostic implications of restrictive left ventricular filling in reperfused anterior acute myocardial
infarction. J Am Coll Cardiol 2001; 37: 793-799.
705. Hillis GS, Moller JE, Pellikka PA, et al. Noninvasive estimation of left ventricular filling pressure by E/e' is a powerful predictor of survival after acute
myocardial infarction. J Am Coll Cardiol 2004; 43: 360-367.
706. Lamas GA, Mitchell GF, Flaker GC, et al. Clinical significance of mitral regurgitation after acute myocardial infarction. Survival and Ventricular
Enlargement Investigators. Circulation 1997; 96: 827-833.
707. Grigioni F, Enriquez-Sarano M, Zehr KJ, et al. Ischemic mitral regurgitation: long-term outcome and prognostic implications with quantitative Doppler
assessment. Circulation 2001; 103: 1759-1764.
708. Bursi F, Enriquez-Sarano M, Nkomo VT, et al. Heart failure and death after myocardial infarction in the community: the emerging role of mitral
regurgitation. Circulation 2005; 111: 295-301.
709. Moller JE, Hillis GS, Oh JK, et al. Prognostic importance of secondary pulmonary hypertension after acute myocardial infarction. Am J Cardiol
2005; 96: 199-203.
710. Obeidat O, Alam M, Divine GW, et al. Echocardiographic predictors of prognosis after first acute myocardial infarction. Am J Cardiol 2004; 94:
1278-1280.
711. St John Sutton M, Pfeffer MA, Plappert T, et al. Quantitative two-dimensional echocardiographic measurements are major predictors of adverse
cardiovascular events after acute myocardial infarction. The protective effects of captopril. Circulation 1994; 89: 68-75.
712. Moller JE, Hillis GS, Oh JK, et al. Left atrial volume: a powerful predictor of survival after acute myocardial infarction. Circulation 2003; 107: 2207-2212.
713. Beinart R, Boyko V, Schwammenthal E, et al. Long-term prognostic significance of left atrial volume in acute myocardial infarction. J Am Coll Cardiol
2004; 44: 327-334.
714. Bigi R, Cortigiani L, Mariani PR, et al. Sustained favorable long-term prognosis of negative stress echocardiography following uncomplicated
myocardial infarction. Am J Cardiol 2002; 90: 149-152.
715. Swinburn JM, Senior R. Myocardial viability assessed by dobutamine stress echocardiography predicts reduced mortality early after acute myocardial
infarction: determining the risk of events after myocardial infarction (DREAM) study. Heart 2006; 92: 44-48.
716. Nijland F, Kamp O, Verhorst PM, et al. Early prediction of improvement in ejection fraction after acute myocardial infarction using low dose dobutamine
echocardiography. Heart 2002; 88: 592-596.
717. Desideri A, Fioretti PM, Cortigiani L, et al. Cost of strategies after myocardial infarction (COSTAMI): a multicentre, international, randomized trial for
cost-effective discharge after uncomplicated myocardial infarction. Eur Heart J 2003; 24: 1630-1639.
718. Desideri A, Fioretti PM, Cortigiani L, et al. Pre-discharge stress echocardiography and exercise ECG for risk stratification after uncomplicated acute
myocardial infarction: results of the COSTAMI-II (cost of strategies after myocardial infarction) trial. Heart 2005; 91: 146-151.
719. Allman KC, Shaw LJ, Hachamovitch R, et al. Myocardial viability testing and impact of revascularization on prognosis in patients with coronary artery
disease and left ventricular dysfunction: a meta-analysis. J Am Coll Cardiol 2002; 39: 1151-1158.
720. Gibbons RJ, Chatterjee K, Daley J, et al. ACC/AHA/ACP-ASIM guidelines for the management of patients with chronic stable angina: a report of the
American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Patients With
Chronic Stable Angina). J Am Coll Cardiol 1999; 33: 2092-2197.
721. Olona M, Candell-Riera J, Permanyer-Miralda G, et al. Strategies for prognostic assessment of uncomplicated first myocardial infarction: 5-year
follow-up study. J Am Coll Cardiol 1995; 25: 815-822.
722. Mahmarian JJ, Mahmarian AC, Marks GF, et al. Role of adenosine thallium-201 tomography for defining long-term risk in patients after acute
myocardial infarction. J Am Coll Cardiol 1995; 25: 1333-1340.
723. Hung J, Moshiri M, Groom GN, et al. Dipyridamole thallium-201 scintigraphy for early risk stratification of patients after uncomplicated myocardial
infarction. Heart 1997; 78: 346-352.
724. Iskander S, Iskandrian AE. Risk assessment using single-photon emission computed tomographic technetium-99m sestamibi imaging. J Am Coll
Cardiol 1998; 32: 57-62.
725. Hachamovitch R, Berman DS, Shaw LJ, et al. Incremental prognostic value of myocardial perfusion single photon emission computed tomography for
the prediction of cardiac death: differential stratification for risk of cardiac death and myocardial infarction. Circulation 1998; 97: 535-543.
726. Acampa W, Spinelli L, Petretta M, et al. Comparison of prognostic value of negative dobutamine stress echocardiography versus single-photon
emission computed tomography after acute myocardial infarction. Am J Cardiol 2005; 96: 13-16.
727. Nakayama M, Tanno M, Yamada H, et al. Correlation of diagnostic accuracy of dipyridamole thallium-201 myocardial scintigraphy and clinical
findings during stress. Jpn Heart J 1994; 35: 281-294.
728. Franken PR, Dendale P, De Geeter F, et al. Prediction of functional outcome after myocardial infarction using BMIPP and sestamibi scintigraphy.
J Nucl Med 1996; 37: 718-722.
729. Fujiwara S, Takeishi Y, Atsumi H, et al. Prediction of functional recovery in acute myocardial infarction: comparison between sestamibi reverse
redistribution and sestamibi/BMIPP mismatch. J Nucl Cardiol 1998; 5: 119-127.
730. Beek AM, Kuhl HP, Bondarenko O, et al. Delayed contrastenhanced magnetic resonance imaging for the prediction of regional functional improvement
after acute myocardial infarction. J Am Coll Cardiol 2003; 42: 895-901.
731. Lombardi M, Kvaerness J, Torheim G, et al. Relationship between function and perfusion early after acute myocardial infarction. Int J Cardiovasc
Imaging 2001; 17: 383-393.
732. Beanlands RS, Nichol G, Huszti E, et al. F-18-fluorodeoxyglucose positron emission tomography imaging-assisted management of patients with
severe left ventricular dysfunction and suspected coronary disease: a randomized, controlled trial (PARR-2). J Am Coll Cardiol 2007; 50: 2002-2012.
733. La Canna G, Rahimtoola SH, Visioli O, et al. Sensitivity, specificity, and predictive accuracies of non-invasive tests, singly and in combination, for
diagnosis of hibernating myocardium. Eur Heart J 2000; 21: 1358-1367.
734. Risk stratification and survival after myocardial infarction. N Engl J Med 1983; 309: 331-336.
735. Urena PE, Lamas GA, Mitchell G, et al. Ejection fraction by radionuclide ventriculography and contrast left ventriculogram. A tale of two techniques.
SAVE Investigators. Survival and Ventricular Enlargement. J Am Coll Cardiol 1999; 33: 180-185.
736. Rashid H, Exner DV, Mirsky I, et al. Comparison of echocardiography and radionuclide angiography as predictors of mortality in patients with left
ventricular dysfunction (studies of left ventricular dysfunction). Am J Cardiol 1999; 84: 299-303.
737. La Rovere MT, Bigger JT, Marcus FI, et al. Baroreflex sensitivity and heart-rate variability in prediction of total cardiac mortality after myocardial
infarction. ATRAMI (Autonomic Tone and Reflexes After Myocardial Infarction) Investigators. Lancet 1998; 351: 478-484.
738. Wilber DJ, Zareba W, Hall WJ, et al. Time dependence of mortality risk and defibrillator benefit after myocardial infarction. Circulation 2004; 109: 1082-
1084.
739. Hamer AW, Takayama M, Abraham KA, et al. End-systolic volume and long-term survival after coronary artery bypass graft surgery in patients with
impaired left ventricular function. Circulation 1994; 90: 2899-2904.
740. Connolly SJ, Gent M, Roberts RS, et al. Canadian implantable defibrillator study (CIDS): a randomized trial of the implantable cardioverter defibrillator
against amiodarone. Circulation 2000; 101: 1297-1302.
741. Moss AJ, Hall WJ, Cannom DS, et al. Improved survival with an implanted defibrillator in patients with coronary disease at high risk for ventricular
arrhythmia. Multicenter Automatic Defibrillator Implantation Trial Investigators. N Engl J Med 1996; 335: 1933-1940.
742. A comparison of antiarrhythmic-drug therapy with implantable defibrillators in patients resuscitated from near-fatal ventricular arrhythmias. The
Antiarrhythmics versus Implantable Defibrillators (AVID) Investigators. N Engl J Med 1997; 337: 1576-1583.
743. Kuck KH, Cappato R, Siebels J, et al. Randomized comparison of antiarrhythmic drug therapy with implantable defibrillators in patients resuscitated
from cardiac arrest : the Cardiac Arrest Study Hamburg (CASH). Circulation 2000; 102: 748-754.
744. Paelinck BP, Vrints CJ, Bax JJ, et al. Relation of B-type natriuretic peptide early after acute myocardial infarction to left ventricular diastolic function
and extent of myocardial damage determined by magnetic resonance imaging. Am J Cardiol 2006; 97: 1146-1150.
745. Richards AM, Nicholls MG, Espiner EA, et al. B-type natriuretic peptides and ejection fraction for prognosis after myocardial infarction. Circulation
2003; 107: 2786-2792.
746. Suzuki S, Yoshimura M, Nakayama M, et al. Plasma level of B-type natriuretic peptide as a prognostic marker after acute myocardial infarction:
a long-term follow-up analysis. Circulation 2004; 110: 1387-1391.
747. Omland T, Persson A, Ng L, et al. N-terminal pro-B-type natriuretic peptide and long-term mortality in acute coronary syndromes. Circulation 2002;
106: 2913-2918.
748. Lee JH, Park HS, Chae SC, et al. Predictors of six-month major adverse cardiac events in 30-day survivors after acute myocardial infarction (from the
Korea Acute Myocardial Infarction Registry). Am J Cardiol 2009; 104: 182-189.
749. Kinjo K, Sato H, Sakata Y, et al. Osaka Acute Coronary Insufficiency Study (OACIS) Group. Relation of C-reactive protein and one-year survival after
acute myocardial infarction with versus without statin therapy. Am J Cardiol 2005; 96: 617-621.
750. Ang DS, Kao MP, Dow E, et al. The prognostic value of high sensitivity troponin T 7 weeks after an acute coronary syndrome. Heart 2012; 98: 1160-
1165.
751. Matsumoto S, Nakatani D, Sakata Y, et al. Elevated serum heart-type fatty acid-binding protein in the convalescent stage predicts long-term outcome
in patients surviving acute myocardial infarction. Circ J 2013; 77: 1026-1032.
752. Hara M, Sakata Y, Nakatani D, et al. Low levels of serum n-3 polyunsaturated fatty acids are associated with worse heart failure-free survival in
patients after acute myocardial infarction. Circ J 2013; 77: 153-162.
753. Matsumoto S, Sakata Y, Nakatani D, et al. A subset of circulating microRNAs are predictive for cardiac death after discharge for acute myocardial
infarction. Biochem Biophys Res Commun 2012; 427: 280-284.
754. Ross J, Gilpin EA, Madsen EB, et al. A decision scheme for coronary angiography after acute myocardial infarction. Circulation 1989; 79: 292-303.
755. Moss AJ, Zareba W, Hall WJ, et al. Prophylactic implantation of a defibrillator in patients with myocardial infarction and reduced ejection fraction.
N Engl J Med 2002; 346: 877-883.
756. Hohnloser SH, Kuck KH, Dorian P, et al. Prophylactic use of an implantable cardioverter-defibrillator after acute myocardial infarction. N Engl J Med
2004; 351: 2481-2488.
757. Bailey JJ, Berson AS, Handelsman H, et al. Utility of current risk stratification tests for predicting major arrhythmic events after myocardial infarction.
J Am Coll Cardiol 2001; 38: 1902-1911.
758. Maggioni AP, Zuanetti G, Franzosi MG, et al. Prevalence and prognostic significance of ventricular arrhythmias after acute myocardial infarction in the
fibrinolytic era. GISSI-2 results. Circulation 1993; 87: 312-322.
759. Zuanetti G, Neilson JM, Latini R, et al. Prognostic significance of heart rate variability in post-myocardial infarction patients in the fibrinolytic era. The
GISSI-2 results. Gruppo Italiano per lo Studio della Sopravvivenza nell' Infarto Miocardico. Circulation 1996; 94: 432-436.
760. Malik M, Camm AJ, Janse MJ, et al. Depressed heart rate variability identifies postinfarction patients who might benefit from prophylactic treatment
with amiodarone: a substudy of EMIAT (The European Myocardial Infarct Amiodarone Trial). J Am Coll Cardiol 2000; 35: 1263-1275.
761. Makikallio TH, Barthel P, Schneider R, et al. Prediction of sudden cardiac death after acute myocardial infarction: role of Holter monitoring in the
modern treatment era. Eur Heart J 2005; 26: 762-769.
762. Denes P, el-Sherif N, Katz R, et al. Prognostic significance of signal-averaged electrocardiogram after thrombolytic therapy and/or angioplasty during
acute myocardial infarction (CAST substudy). Cardiac Arrhythmia Suppression Trial (CAST) SAECG Substudy Investigators. Am J Cardiol 1994; 74:
216-220.
763. el-Sherif N, Denes P, Katz R, et al. Definition of the best prediction criteria of the time domain signal-averaged electrocardiogram for serious arrhythmic
events in the postinfarction period. The Cardiac Arrhythmia Suppression Trial/Signal-Averaged Electrocardiogram (CAST/SAECG) Substudy
Investigators. J Am Coll Cardiol 1995; 25: 908-914.
764. Hohnloser SH, Ikeda T, Bloomfield DM, et al. T-wave alternans negative coronary patients with low ejection and benefit from defibrillator implantation.
Lancet 2003; 362: 125-126.
765. Zoni-Berisso M, Molini D, Mela GS, et al. Value of programmed ventricular stimulation in predicting sudden death and sustained ventricular tachycardia
in survivors of acute myocardial infarction. Am J Cardiol 1996; 77: 673-680.
766. Buxton AE, Lee KL, Fisher JD, et al. A randomized study of the prevention of sudden death in patients with coronary artery disease. Multicenter
Unsustained Tachycardia Trial Investigators. N Engl J Med 1999; 341: 1882-1890.
767. Daubert JP, Zareba W, Hall WJ, et al. Predictive value of ventricular arrhythmia inducibility for subsequent ventricular tachycardia or ventricular
fibrillation in Multicenter Automatic Defibrillator Implantation Trial (MADIT) II patients. J Am Coll Cardiol 2006; 47: 98-107.
768. Nakatani D, Sakata Y, Sato H, et al. Osaka Acute Coronary Insufficiency Study (OACIS) Group. Clinical impact of metabolic syndrome and its
additive effect with smoking on subsequent cardiac events after acute myocardial infarction. Am J Cardiol 2007; 99: 885-889.
769. Nakatani D, Sakata Y, Suna S, et al; Osaka Acute Coronary Insufficiency Study (OACIS) Investigators. Incidence, predictors, and subsequent
mortality risk of recurrent myocardial infarction in patients following discharge for acute myocardial infarction. Circ J 2013; 77: 439-446.
770. Balady GJ, Fletcher BJ, Froelicher EF, et al. Cardiac rehabilitation programs: a statement for healthcare professionals from the American Heart
Association. Circulation 1994; 90: 1602-1610.
771. Wenger NK, Froelicher ES, Smith LK, et al. Clinical Practice Guidelines No. 17: Cardiac Rehabilitation as Secondary Prevention. U.S. Department of
Health and Human Services, Public Health Service, Agency for Health Care Policy and Research, National Heart, Lung and Blood Institute, 1995.
AHCPR Publication 96-0672.
772. Leon AS, Franklin BA, Costa F, et al. Cardiac rehabilitation and secondary prevention of coronary heart disease: an American Heart Association
scientific statement from the Council on Clinical Cardiology (Subcommittee on Exercise, Cardiac Rehabilitation, and Prevention) and the Council on
Nutrition, Physical Activity, and Metabolism (Subcommittee on Physical Activity), in collaboration with the American association of Cardiovascular
and Pulmonary Rehabilitation. Circulation 2005; 111: 369-376.
773. Ades PA. Cardiac rehabilitation and secondary prevention of coronary heart disease. N Engl J Med 2001; 345: 892-902.
774. Taylor RS, Brown A, Ebrahim S, et al. Exercise-based rehabilitation for patients with coronary heart disease: systematic review and meta-analysis of
randomized controlled trials. Am J Med 2004; 116: 682-692.
775. Lawler PR, Filion KB, Eisenberg MJ. Efficacy of exercise-based cardiac rehabilitation post-myocardial infarction: a systematic review and meta-
analysis of randomized controlled trials. Am Heart J 2011; 162: 571-584.e572.
776. Haykowsky M, Scott J, Esch B, et al. A meta-analysis of the effects of exercise training on left ventricular remodeling following myocardial infarction:
start early and go longer for greatest exercise benefits on remodeling. Trials 2011; 12: 92.
777. Antman EM, Hand M, Armstrong PW, et al. 2007 Focused Update of the ACC/AHA 2004 Guidelines for the Management of Patients With
ST-Elevation Myocardial Infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines:
developed in collaboration With the Canadian Cardiovascular Society endorsed by the American Academy of Family Physicians: 2007 Writing Group
to Review New Evidence and Update the ACC/AHA 2004 Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction, Writing
on Behalf of the 2004 Writing Committee. Circulation 2008; 117: 296-329.
778. Smith SC, Benjamin EJ, Bonow RO, et al. AHA/ACCF Secondary Prevention and Risk Reduction Therapy for Patients with Coronary and other
Atherosclerotic Vascular Disease: 2011 update: a guideline from the American Heart Association and American College of Cardiology Foundation.
Circulation 2011; 124: 2458-2473.
779. Yoshida T, Yoshida K, Yamamoto C, et al. Effects of a two-week, hospitalized phase II cardiac rehabilitation program on physical capacity, lipid
profiles and psychological variables in patients with acute myocardial infarction. Jpn Circ J 2001; 65: 87-93.
780. 循環器病の診断と治療に関するガイドライン．心血管疾患におけるリハビリテーションに関するガイドライン（2007年改訂版）．http://www.j-
circ.or.jp/guideline/pdf/JCS2007_nohara_d.pdf（2012年12月閲覧）
781. Izawa K, Hirano Y, Yamada S, et al. Improvement in physiological outcomes and health-related quality of life following cardiac rehabilitation in
patients with acute myocardial infarction. Circ J 2004; 68: 315-320.
782. Suzuki S, Takaki H, Yasumura Y, et al. Assessment of quality of life with 5 different scales in patients participating in comprehensive cardiac
rehabilitation after acute myocardial infarction. Circ J 2005; 69: 1527-1534.
783. Kida K, Osada N, Akashi YJ, et al. The exercise training effects of skeletal muscle strength and muscle volume to improve functional capacity in
patients with myocardial infarction. Int J Cardiol 2008; 129: 180-186.
784. Sumide T, Shimada K, Ohmura H, et al. Relationship between exercise tolerance and muscle strength following cardiac rehabilitation: comparison
of patients after cardiac surgery and patients with myocardial infarction. J Cardiol 2009; 54: 273-281.
785. Kamakura T, Kawakami R, Nakanishi M, et al. Efficacy of out-patient cardiac rehabilitation in low prognostic risk patients after acute myocardial
infarction in primary intervention era. Circ J 2011; 75: 315-321.
786. Goto Y, Itoh H, Adachi H, et al. Use of exercise cardiac rehabilitation after acute myocardial infarction. Circ J 2003; 67: 411-415.
787. Goto Y, Saito M, Iwasaka T, et al. Poor implementation of cardiac rehabilitation despite broad dissemination of coronary interventions for acute
myocardial infarction in Japan: a nationwide survey. Circ J 2007; 71: 173-179.
788. 中西道郎，長山雅俊，安達仁，他．我が国における急性心筋梗塞後心臓リハビリテーション実施率の動向：全国実態調査．心臓リハ 2011; 16: 188-192.
789. Fletcher GF, Balady GJ, Amsterdam EA, et al. Exercise standards for testing and training: a statement for healthcare professionals from the
American Heart Association. Circulation 2001; 104: 1694-1740.
790. Sanderson BK, Southard D, Oldridge N, et al. AACVPR consensus statement. Outcomes evaluation in cardiac rehabilitation/secondary prevention
programs: improving patient care and program effectiveness. J Cardiopulm Rehabil 2004; 24: 68-79.
791. Balady GJ, Williams MA, Ades PA, et al. AHA/AACVPR Scientific Statement. Core components of cardiac rehabilitation/ secondary prevention
programs: 2007 Update. A Scientific Statement From the American Heart Association Exercise, Cardiac Rehabilitation, and Prevention Committee,
the Council on Clinical Cardiology; the Councils on Cardiovascular Nursing, Epidemiology and Prevention, and Nutrition, Physical Activity, and
Metabolism; and the American Association of Cardiovascular and Pulmonary Rehabilitation. Circulation 2007; 115: 2675-2682.
792. Chobanian AV, Lille RD, Tercyak A, et al. The metabolic and hemodynamic effects of prolonged bed rest in normal subjects. Circulation 1974; 49:
551-559.
793. Cannon CP, Hand MH, Bahr R, et al. Critical pathways for management of patients with acute coronary syndromes: an assessment by the National
Heart Attack Alert Program. Am Heart J 2002; 143: 777-789.
794. 循環器病の診断と治療に関するガイドライン．心血管疾患におけるリハビリテーションに関するガイドライン（2012年改訂版）．http://www.j-
circ.or.jp/guideline/pdf/JCS2012_nohara_h.pdf（2012年12月閲覧）
795. Gibbons RJ, Balady GJ, Bricker JT, et al. ACC/AHA 2002 guideline update for exercise testing: summary article: a report of the American College of
Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Update the 1997 Exercise Testing Guidelines). Circulation
2002; 106: 1883-1892.
796. Senaratne MP, Smith G, Gulamhusein SS. Feasibility and safety of early exercise testing using the Bruce protocol after acute myocardial infarction.
J Am Coll Cardiol 2000; 35: 1212-1220.
797. Goto Y, Sumida H, Ueshima K, et al. Safety and implementation of exercise testing and training after coronary stenting in patients with acute
myocardial infarction. Circ J 2002; 66: 930-936.
798. Williams MA, Haskell WL, Ades PA, et al. Resistance exercise in individuals with and without cardiovascular disease: 2007 update: a scientific
statement from the American Heart Association Council on Clinical Cardiology and Council on Nutrition, Physical Activity, and Metabolism.
Circulation 2007; 116: 572-584.
799. Wilke NA, Sheldahl LM, Tristani FE, et al. The safety of staticdynamic effort soon after myocardial infarction. Am Heart J 1985; 110: 542-545.
800. Arthur HM, Gunn E, Thorpe KE, et al. Effect of aerobic vs combined aerobic-strength training on 1-year, post-cardiac rehabilitation outcomes in
women after a cardiac event. J Rehabil Med 2007; 39: 730-735.